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| 1. |  | DE CARVALHO NUNES, L.; STEGELMEIER, B. L.; COOK, D.; PFISTER, J. A.; GARDNER, D. R.; RIET-CORREA, F.; WEICH, K. D. Clinical and pathological comparison of Astragalus lentiginosus and Ipomoea carnea poisoning in goats. Toxicon, 5 December, 2019, Volume 171, Pages 20-28. Doi: 10.1016/j.toxicon.2019.09.016 Article history: Received 12 July 2019; Received in revised form 12 September 2019; Accepted 16 September 2019; Available online 19 September 2019.| Biblioteca(s): INIA Las Brujas. |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha actual : |
17/10/2014 |
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Actualizado : |
03/10/2019 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Circulación / Nivel : |
B - 2 |
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Autor : |
KALPOKAS, I.; PERDIGON, F.; RIVERO, R.; TALMON, M.; SARTORE, I.; VIÑOLES, C. |
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Afiliación : |
CAROLINA VIÑOLES GIL, Instituto Nacional de Investigación Agropecuaria (INIA), Uruguay. |
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Título : |
Effect of a povidone-iodine intrauterine infusion on progesterone levels and endometrial steroid receptor expression in mares. |
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Fecha de publicación : |
2010 |
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Fuente / Imprenta : |
Acta Veterinaria Scandinavica, 2010, v.52, No.1, p.66-73. OPEN ACCESS |
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ISSN : |
0044-605X |
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DOI : |
10.1186/1751-0147-52-66 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received: 15 August 2010 / Accepted: 16 December 2010 / Published: 16 December 2010. |
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Contenido : |
BACKGROUND.
Intrauterine infusions have been widely used for the treatment of endometritis in the mare. Nevertheless, their consequences on endocrine and endometrial molecular aspects are unknown. We studied the effect of a 1% povidone-iodine solution intrauterine infusion on progesterone levels, endometrial histology and estrogen (ERα) and progesterone (PR) receptor distribution by immunohistochemistry.Methods: Fourteen healthy mares were used in this study. Estruses were synchronized and seven mares were treated with intrauterine infusions at days 0 and 2 post ovulation of two consecutive estrous cycles. Uterine biopsy samples were taken on days 6 and 15 post ovulation.Results: The treatment did not induce an inflammatory response indicating endometritis, neither affected the ERα. However, it reduced the percentage of PR positive cells (PPC) on day 6 (deep glandular epithelium, control: 95.7 vs. infused: 61.5, P < 0.05). Treated mares tended to have lower progesterone levels on day 2 (3.9 ng/ml vs. 6.6 ng/ml, P = 0.07), and higher levels on day 15 compared with controls (4.4 ng/ml vs. 1.3 ng/ml, P = 0.07).Conclusion: a 1% povidone-iodine infusion during days 0 and 2 post ovulation in healthy mares did not induce histological changes indicating endometritis, but altered progesterone concentrations and reduced the expression of endometrial PR at day 6 without affecting the ERα. These changes could reduce embryo survival.
© 2010 Kalpokas et al; licensee BioMed Central Ltd. MenosBACKGROUND.
Intrauterine infusions have been widely used for the treatment of endometritis in the mare. Nevertheless, their consequences on endocrine and endometrial molecular aspects are unknown. We studied the effect of a 1% povidone-iodine solution intrauterine infusion on progesterone levels, endometrial histology and estrogen (ERα) and progesterone (PR) receptor distribution by immunohistochemistry.Methods: Fourteen healthy mares were used in this study. Estruses were synchronized and seven mares were treated with intrauterine infusions at days 0 and 2 post ovulation of two consecutive estrous cycles. Uterine biopsy samples were taken on days 6 and 15 post ovulation.Results: The treatment did not induce an inflammatory response indicating endometritis, neither affected the ERα. However, it reduced the percentage of PR positive cells (PPC) on day 6 (deep glandular epithelium, control: 95.7 vs. infused: 61.5, P < 0.05). Treated mares tended to have lower progesterone levels on day 2 (3.9 ng/ml vs. 6.6 ng/ml, P = 0.07), and higher levels on day 15 compared with controls (4.4 ng/ml vs. 1.3 ng/ml, P = 0.07).Conclusion: a 1% povidone-iodine infusion during days 0 and 2 post ovulation in healthy mares did not induce histological changes indicating endometritis, but altered progesterone concentrations and reduced the expression of endometrial PR at day 6 without affecting the ERα. These changes could reduce embryo survival.
© 2010 Kalpokas et al; licensee BioMe... Presentar Todo |
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Palabras claves : |
ANIMAL DISEASE. |
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Thesagro : |
AGENTES INFECCIOSOS; ENDOMETRITIS; ENFERMEDADES DE LOS ANIMALES. |
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Asunto categoría : |
L73 Enfermedades de los animales |
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URL : |
http://www.actavetscand.com/content/52/1/66
http://www.ainfo.inia.uy/digital/bitstream/item/3575/1/Vinoles-C.-2010.-Acta-Veterinaria-Scandinavica-v.521-p.66.pdf
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Marc : |
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001 1051173
005 2019-10-03
008 2010 bl uuuu u00u1 u #d
022 $a0044-605X
024 7 $a10.1186/1751-0147-52-66$2DOI
100 1 $aKALPOKAS, I.
245 $aEffect of a povidone-iodine intrauterine infusion on progesterone levels and endometrial steroid receptor expression in mares.$h[electronic resource]
260 $c2010
500 $aArticle history: Received: 15 August 2010 / Accepted: 16 December 2010 / Published: 16 December 2010.
520 $aBACKGROUND. Intrauterine infusions have been widely used for the treatment of endometritis in the mare. Nevertheless, their consequences on endocrine and endometrial molecular aspects are unknown. We studied the effect of a 1% povidone-iodine solution intrauterine infusion on progesterone levels, endometrial histology and estrogen (ERα) and progesterone (PR) receptor distribution by immunohistochemistry.Methods: Fourteen healthy mares were used in this study. Estruses were synchronized and seven mares were treated with intrauterine infusions at days 0 and 2 post ovulation of two consecutive estrous cycles. Uterine biopsy samples were taken on days 6 and 15 post ovulation.Results: The treatment did not induce an inflammatory response indicating endometritis, neither affected the ERα. However, it reduced the percentage of PR positive cells (PPC) on day 6 (deep glandular epithelium, control: 95.7 vs. infused: 61.5, P < 0.05). Treated mares tended to have lower progesterone levels on day 2 (3.9 ng/ml vs. 6.6 ng/ml, P = 0.07), and higher levels on day 15 compared with controls (4.4 ng/ml vs. 1.3 ng/ml, P = 0.07).Conclusion: a 1% povidone-iodine infusion during days 0 and 2 post ovulation in healthy mares did not induce histological changes indicating endometritis, but altered progesterone concentrations and reduced the expression of endometrial PR at day 6 without affecting the ERα. These changes could reduce embryo survival. © 2010 Kalpokas et al; licensee BioMed Central Ltd.
650 $aAGENTES INFECCIOSOS
650 $aENDOMETRITIS
650 $aENFERMEDADES DE LOS ANIMALES
653 $aANIMAL DISEASE
700 1 $aPERDIGON, F.
700 1 $aRIVERO, R.
700 1 $aTALMON, M.
700 1 $aSARTORE, I.
700 1 $aVIÑOLES, C.
773 $tActa Veterinaria Scandinavica, 2010$gv.52, No.1, p.66-73. OPEN ACCESS
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